| Rayovac | Middleton | 1906 |
| Reebok | Boston | 1895 |
| Regions Financial Corporation | Birmingham | 13 de julho de 1971 |
| Remington Arms | Madison | 1816 |
| Rite Aid | Filadélfia, East Pennsboro Township | 1962 |
| Roku | Los Gatos | outubro 2002 |
| Rough Draft Studios | Glendale | 1990 |
| S. C. Johnson & Son | Racine | 1886 |
| Salesforce | Salesforce Tower, São Francisco | 3 de fevereiro de 1999 |
| Sara Lee Corporation | Downers Grove | 1939 |
| SAS | Cary | 1976 |
| Schecter Guitar Research | Los Angeles | 1976 |
| Sealy Corporation | Trinity | 1881 |
| Shelby SuperCars | West Richland | 1999 |
| Silicon Graphics | Sunnyvale, Mountain View | 9 de novembro de 1981 |
| Silver Lake | Menlo Park | 1999 |
| Six Flags | Arlington | 1961 |
| Skechers | Manhattan Beach | 1992 |
| Smith & Wesson | Springfield | 1852 |
| Smithfield Foods | Smithfield | 1936 |
| SoundHound | Santa Clara | setembro 2005 |
| Spansion | Sunnyvale | 2003 |
| Staples Inc. | Framingham | 1986 |
| Starwood | White Plains | 1930 |
| Steak 'n Shake | Indianápolis | 1934 |
| Stellantis North America | Chrysler Headquarters and Technology Center | 28 de abril de 2009 |
| Storage Technology Corporation | Louisville | 1969 |
| Strategic Simulations | Sunnyvale | 1979 |
| Substack | — | 29 de novembro de 2017 |
| Subway | Milford | 28 de agosto de 1965 |
| Sumisho Air Lease | Los Angeles | 2010 |
| Sunkist Growers | Los Angeles | 29 de agosto de 1893 |
| Supreme | Nova Iorque | abril 1994 |
| Synaptics | Santa Clara | 1986 |
| T-Mobile US | Bellevue | 2001 |
| T. Rowe Price | Baltimore | 1937 |
| Taser International | Scottsdale | setembro 1993 |
| Tesoro Corporation | — | 1968 |
| The Bank of New York Mellon | Nova Iorque | 2007 |
| The Cigna Group | Bloomfield | 1982 |
| The Gillette Company | — | 28 de setembro de 1901 |
| The New York Times Company | New York Times Building, Nova Iorque | 18 de setembro de 1851 |
| The Vanguard Group | Malvern | 1 de maio de 1975 |
| TIBCO Software | Palo Alto | 1997 |
| TiVo Corporation | Santa Clara, São José | 1983 |
| TJX Companies | Framingham | 1956 |
| Tommy Hilfiger | Nova Iorque, Amsterdã | 1985 |
| TopCoder | São Francisco | 2001 |